FAQ
Physiologic Insulin Resensitization (PIR) Therapy
What is Physiologic Insulin Resensitization (PIR)?
PIR is an innovative treatment designed to help the body use insulin more effectively. Instead of just lowering blood sugar, PIR focuses on restoring your cells’ sensitivity to insulin, which addresses the root cause of insulin resistance.
How is PIR different from standard insulin therapy?
Traditional insulin therapy delivers insulin in large doses to control blood sugar. PIR uses small, physiologic doses of insulin given in a pulsed pattern through an IV. This mimics how a healthy pancreas releases insulin, which can improve how your body metabolizes carbohydrates, fats, and proteins.
Who can benefit from PIR?
PIR may benefit patients with:
- Type 2 diabetes
- Metabolic syndrome
- Pre-diabetes
- Peripheral neuropathy
- Other complications related to insulin resistance
Your provider will determine if you are a good candidate.
What happens during a PIR session?
During a session, you sit comfortably while a small IV delivers insulin in timed pulses. At the same time, you’ll consume a small amount of glucose to stimulate your body’s natural response. Treatments usually last 2–3 hours.
How often do I need treatment?
Most patients start with weekly treatments. Over time, the frequency may be reduced based on your response and improvement. Each treatment plan is personalized.
Is PIR safe?
Yes. PIR is FDA-cleared for the administration of insulin and glucose in this way. Treatments are performed under medical supervision, and your blood sugar levels are monitored closely throughout the session.
Will PIR replace my current medications?
PIR is designed to work alongside your current treatment plan. Some patients may reduce their need for medications over time, but changes should only be made under your provider’s guidance.
How soon will I see results?
Some patients notice improvements in energy, circulation, or neuropathy symptoms after just a few sessions. For others, benefits build gradually over weeks or months of consistent therapy.
Does insurance cover PIR therapy?
Coverage varies depending on your insurance provider and plan. Our office can help verify your benefits and discuss payment options if needed.
How do I get started?
Schedule a consultation with our clinic. We’ll review your medical history, perform any necessary testing, and create a personalized treatment plan to determine if PIR is right for you.